Montelukast: • Antagonizes the proinfalmmatory & proasthmatic activies • Can be used as first line therapy for AR, with comprehensive improvement of the nasal & ocular symptoms & the quality of life in AR patients. Levocetirizine: • Is a 2nd generation non sedative antihistaminic agent that has been demonstrated to be safe & effective for treating allergic disease • Does not bind significantly to the brain H1Rs & does not induce significant sedation Indication: • Asthma • Perennial Allergic rhinitis (PAR) • Seasonal Flu • Seasonal Allergic rhinitis (SAR) • Respiratory tract allergies • Allergic rhinitis • Nasal & respiratory allergies • Cough and cold • Chronic obstructive pulmonary disease (COPD)